The HEPATITIS D virus (HDV) is an RNA defective virus which
has no independent existence,it requires HBV virus for replication and has got
same mode of transmission.It can infect those with HBV and can also cause
superinfection on chronic carriers for HBV
Infection is self limiting along with HBV. Simultaneous
infection with HBV and HCV Leads on to rapid progressive Hepatitis leading on
to cirrhosis
Mode of transmission is similar to HBV
Investigations
HDV virus contain a single antigen to which body makes
anti-HDV antibody, delta antigen appears in blood transiently, diagnosis depends
on anti-HDV. Antibody usually disappears after 2 months
Super infection produce high titres of anti-HDV.
Management
Effective management of hepatitis B effectively prevents
hepatitis D