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Friday, 9 November 2012

HEPATITIS D (DELTA VIRUS)


The HEPATITIS D virus (HDV) is an RNA defective virus which has no independent existence,it requires HBV virus for replication and has got same mode of transmission.It can infect those with HBV and can also cause superinfection on chronic carriers for HBV

Infection is self limiting along with HBV. Simultaneous infection with HBV and HCV Leads on to rapid progressive Hepatitis leading on to cirrhosis
Mode of transmission is similar to HBV

Investigations

HDV virus contain a single antigen to which body makes anti-HDV antibody, delta antigen appears in blood transiently, diagnosis depends on anti-HDV. Antibody usually disappears after 2 months
Super infection produce high titres of anti-HDV.

Management

Effective management of hepatitis B effectively prevents hepatitis D

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